Monday, March 31, 2014

GlobalCollect Introduces Business Intelligence Solution to Optimize Payments for Merchants

Pilot users see immediate impact on business results

AMSTERDAM. - Monday, March 31st 2014 [ME NewsWire]

(BUSINESS WIRE) GlobalCollect, the world’s most knowledgeable payment service provider, today announced Elevate Data Services, a comprehensive Business Intelligence solution designed specifically for online payments and chargebacks. Elevate was conceived in response to the unique need for insights expressed by GlobalCollect’s clients, and developed in close cooperation with GlobalCollect’s Customer Advisory Board (GCAB), which includes many leading international eCommerce companies. With Elevate, GlobalCollect merchants can now apply advanced data analytics and visualization to their unstructured payments data, transforming it into a rich source of strategic insights that help optimize their online business and drive sales.

As global online commerce continues to expand and emerging economies in Asia, Latin America and Africa increasingly join the global online marketplace, international eCommerce companies are booming. However, with each additional market comes additional complexity, from local payment preferences and currencies, to new fraud environments. In order to effectively manage this complexity and take maximum advantage of opportunities for growth, merchants need to cut through the clutter of raw payment data and find the patterns, trends and issues that need their attention most. With Elevate, they now have a comprehensive and sophisticated tool that organizes unstructured data into targeted dashboards and lets them interact with the data in order to find exactly those insights that will help them to make the decisions that accelerate the growth of their business.

Elevate combines GlobalCollect’s payments knowledge with strategic guidance from leading international eCommerce companies and the industry-leading data visualization platform by Tableau Software*, to create a payments intelligence solution consisting of highly interactive management dashboards that answer real business questions. Centered around 5 key performance areas, these dashboards reveal the types of payments performance insights that let merchants quickly and easily identify trends and patterns, opportunities for optimization, and issues that need immediate attention. The 5 key performance areas in Elevate are:

    Your Performance, which presents a holistic view of payments performance across the 6 KPI’s that merchants indicate are most relevant to them;
    Commercial Insights, which provides insight into consumer payment behavior;
    Authorization Rates, which reveals key authorization trends such as card performance and rejection reasons;
    Payment Funnel, which provides an overview of the payment stages a transaction goes through; and
    Chargeback Insights, which helps prevent fraud through chargeback analysis

Elevate is browser-based, making it time, place and device agnostic, and was designed to support multiple functions within international eCommerce organizations. For senior management, Elevate provides access to comprehensive reports on global payments performance and trends, that help guide strategic decisions and grow revenue. Payment managers benefit from the granular insights they need to identify opportunities and optimize conversions on a day-to-day basis. Fraud managers can analyze chargeback data for unexpected patterns, and take swift and targeted measures to counter fraud and lower costs.

“Our customers rely on us to not only process their payments, but to help them realize their full commercial potential through conversion optimization, international expansion, and fraud reduction,” said Thomas P. Staudt, Chief Executive Officer of GlobalCollect. “When it comes to success in international online commerce, knowledge is power. With Elevate, we give our merchants the knowledge they need to keep improving and optimizing their business and reach that maximum potential.”

About GlobalCollect

GlobalCollect is the world’s most knowledgeable global Payment Service Provider, processing international eCommerce payments for more than 600 of the world’s most recognized eCommerce brands. For more information please visit: http://www.globalcollect.com

*Gartner: Magic Quadrant for Business Intelligence and Analytics Platforms, https://www.gartner.com/doc/2668318

Contacts

GlobalCollect

Jurriaan Trommels

Senior PR & Communications Manager

Mob. +31 630 161420

E-Mail: press@globalcollect.com

Web: www.globalcollect.com

Heritage Global Partners Appointed to Manage Global Private Treaty Sale of Maintenance Railway Locomotives

Bids for Railway Assets Being Accepted Immediately, With Sale Slated to End June 18, 2014

SAN DIEGO & BARCELONA, Spain - Monday, March 31st 2014 [ME NewsWire]

(BUSINESS WIRE) Heritage Global Partners (“HGP”), a global leader in asset advisory and auction services and a subsidiary of Heritage Global Inc. (OTCQB:HGBL), today announced that it has been retained to manage the upcoming sale of four maintenance railway locomotives, which are presently located in Spain. Bids are being accepted for these well maintained railway transportation assets. The Railway Locomotive Global Private Treaty Sale is scheduled to end June 18, 2014 at 10 am CET.

Additional details and specifications regarding the four COMSA Rail Transport & GMF maintenance railway locomotives are contained in three below links.

    Plasser & Theurer Dynamic Tamping Express (Type 09-3X; Track Gauge 1435; Manufactured in 2000)

    Matisa Continuous Advance Levelling and Lining Tamper (Type B50 DF; Track Gauge 1435; Manufactured in 1992)

    Electroputere Locomotives (Type ST 43/LDE-2100; Track Gauge 1435; Manufactured in 1977/1984)

“Heritage Global’s unique global private treaty sale features four maintenance locomotives that can be utilized by railway organizations around the world,” stated Heritage Global Partners, Head of Sales Spain, Miguel Garcia. “We expect the sale of these quality transportation assets to appeal to a very wide range of potential buyers.”

In the case of international buyers, Heritage Global Partners is pleased to offer our valued customers full-service shipping and logistics services. Our seasoned staff, including riggers and shipping agents, will assist purchasers by remaining on-site to ensure that all necessary paperwork, documents and shipping arrangements are handled in a smooth and efficient manner. HGP has conducted thousands of capital asset transactions and plant closures and is uniquely skilled in all nuances of the transition from seller to buyer.

Led by auction industry pioneers Ross and Kirk Dove, Heritage Global Partners is one of the leading worldwide asset advisory and auction services firms, assisting companies with buying and selling assets. HGP specializes in asset brokerage, inspection, and valuations, industrial equipment and real estate auctions, and much more. HGP is a subsidiary of Heritage Global Inc.

Contacts

Heritage Global Partners

Miguel Garcia, +34 622 230 290 (mobile)

mgarcia@hgpsubasta.com

via Skype: mgarciabcn



JCIR

Robert Rinderman or Jennifer Neuman, 212-835-8500

HGP@jcir.com







Permalink: http://www.me-newswire.net/news/10509/en

Toshiba Launches Wireless Power Receiver IC Supporting Quick Charging

TOKYO - Monday, March 31st 2014 [ME NewsWire]

(BUSINESS WIRE)-- Toshiba Corporation (TOKYO:6502) today announced the launch of “TC7763WBG”, a wireless power receiver IC for mobile equipment that is compatible with the Qi1 standard defined by the Wireless Power Consortium (WPC). This includes smartphones and mobile accessories. The IC realizes a charging time equivalent to charging with a cable. Mass production shipments start today.

Wireless charging allows adoption of an insulated case free of exposed charging ports, an advantage of that is stimulating demand for waterproof portable products, such as smartphones and wireless video game controllers. High power transmission is also required for wireless chargers to reduce charging time.

“TC7763WBG” adopts optimized circuit design to increase maximum output power to 5 Watts, comparable with a cable, enhancing applicability.

Toshiba is expanding its line-up of wireless power receiver IC.

Key Features

    Maximum 5-watt output power.
    95% maximum power conversion efficiency
    Integrates protocol authentication circuit for power transfers
    Supports foreign object detection (FOD) functions.
    Adopts compatible pin assignments with “TC7761WBG”, which supports maximum 3.5 Watts, allowing replacement without any need to change PCB design.

Applications

Mobile equipment, such as smartphones, mobile accessories, and wireless game controllers


Main Specifications

Parts Number
         

TC7763WBG

Transmitting/Receiving
         

Receiver IC

Transmission Method
         

Electromagnetic induction method

Maximum Output Power
         

5W

Package
         

WCSP28


Note: 1. The international standard for inductive electrical power transfer over distances of up to 4 cm, defined by the Wireless Power Consortium.

Customer Inquiries: Mixed Signal IC Sales and Marketing Department Tel: +81-44-548-2821

Information in this document, including product prices and specifications, content of services and contact information, is current on the date of the announcement but is subject to change without prior notice.

About Toshiba

Toshiba is a world-leading diversified manufacturer, solutions provider and marketer of advanced electronic and electrical products and systems. Toshiba Group brings innovation and imagination to a wide range of businesses: digital products, including LCD TVs, notebook PCs, retail solutions and MFPs; electronic devices, including semiconductors, storage products and materials; industrial and social infrastructure systems, including power generation systems, smart community solutions, medical systems and escalators & elevators; and home appliances.

Toshiba was founded in 1875, and today operates a global network of more than 590 consolidated companies, with 206,000 employees worldwide and annual sales surpassing 5.8 trillion yen (US$61 billion). Visit Toshiba's web site at www.toshiba.co.jp/index.htm

Photos/Multimedia Gallery Available: http://www.businesswire.com/multimedia/home/20140330005047/en/

Contacts
Media Inquiries:
Toshiba Corporation
Semiconductor & Storage Products Company
Takashi Mochizuki, +81-3-3457-4963
semicon-NR-mailbox@ml.toshiba.co.jp







Permalink: http://www.me-newswire.net/news/10499/en

Sunday, March 30, 2014

General Cable Updates First Quarter Outlook

ME Newswire / Businesswire

HIGHLAND HEIGHTS, Ky - Saturday, March 29th 2014

    Expects lower first quarter adjusted operating income principally due to uncertainty in Venezuela, extreme weather in North America and lower copper prices
    Adjusted operating income for 2014 anticipated to be at around the low end of previous range of $260 to $320 million
    Repurchased 2% of common shares or $30 million in the first quarter

General Cable Corporation (NYSE: BGC) announced today first quarter adjusted operating income is expected to be below the Company’s previously communicated outlook. The Company now expects to generate adjusted operating income in the range of $17 to $27 million in the first quarter of 2014. The Company’s previous outlook was $30 to $45 million.

Relative to the Company’s previously communicated first quarter outlook, business activity in Venezuela has significantly lagged expectations due to the ongoing social unrest and uncertainty surrounding the recently announced price controls. In North America, operating results are expected to lag management’s expectations principally due to the extreme winter weather experienced across the region as unit volume is anticipated to be in the range of 4-6% lower than previously communicated for the first quarter. Finally, first quarter operating results are expected to be impacted by selling higher average cost inventory into a lower metal price environment as copper prices rapidly declined during the month of March. The COMEX spot copper price as of March 26 was $3.01 which was down 9% as compared to the previously communicated copper price assumption of $3.32.

Given the current lower copper price environment, the ongoing uncertainty in Venezuela and the weather related issues in North America, the Company anticipates generating adjusted operating income for 2014 at around the low end of its previously communicated range of $260 to $320 million. Going forward into the second quarter, the Company continues to expect a sharp improvement in operating results as construction activity accelerates and installation work on submarine projects in the North and Baltic Seas resumes. The current full year outlook now assumes copper and aluminum (Midwest Premium) prices of $3.01 and $0.96, respectively, and approximately $30 million of operating income from Venezuela which is down from the previously communicated expectation of $45 million. The current outlook for Venezuela assumes the official foreign currency exchange rate of 6.3 Bolivars per U.S. dollar.

The Company repurchased 1.0 million shares, 2% of its common shares or approximately $31 million during the first quarter under its $125 million share repurchase authorization which is set to expire at the end of the year. Under its current program, the Company has repurchased 1.6 million shares, 3% of its common shares or $50 million. The Company may utilize the remaining $75 million buyback authorization in the context of economic conditions as well as the then prevailing market price of the common stock of the Company, regulatory requirements, financial covenants and alternative capital investments.

General Cable Corporation will host an Investor Day from 1:00 p.m. to 5:00 p.m. on Thursday, April 3, 2014 at The Grand Hyatt in New York City. Financial analysts and investors may register to attend by contacting Angel Price by email at aprice@generalcable.com. Space is limited and pre-registration is required for admittance to the event. For those unable to attend, General Cable will provide a live audio webcast of the speaker presentations, accessible from www.generalcable.com beginning at 1:00 p.m. ET on Thursday, April 3, 2014. The webcast will also be available for replay.

General Cable Corporation (NYSE:BGC), a Fortune 500 Company, is a global leader in the development, design, manufacture, marketing and distribution of copper, aluminum and fiber optic wire and cable products and systems for the energy, industrial, specialty, construction and communications markets. Visit our website at www.generalcable.com.

Cautionary Statement Regarding Forward-Looking Statements Certain statements in this press release are forward-looking statements that involve risks and uncertainties, predict or describe future events or trends and that do not relate solely to historical matters. Forward looking statements include, among others, expressed expectations with regard to the following: “believe,” “expect,” “may,” “will,” “anticipate,” “intend,” “estimate,” “project,” “plan,” “assume,” “seek to” or other similar expressions, although not all forward-looking statements contain these identifying words. Actual results may differ materially from those discussed in forward-looking statements as a result of factors, risks and uncertainties over many of which we have no control. These factors include, but are not limited to: the economic strength and competitive nature of the geographic markets that the Company serves; our ability to increase manufacturing capacity and productivity; our ability to increase our selling prices during periods of increasing raw material costs; our ability to service, and meet all requirements under, our debt, and to maintain adequate domestic and international credit facilities and credit lines; our ability to establish and maintain internal controls; the impact of unexpected future judgments or settlements of claims and litigation; impact of foreign currency fluctuations, compliance with U.S. and foreign laws, including the Foreign Corrupt Practices Act; our ability to implement and make appropriate, timely and beneficial decisions as to when, how and if to purchase shares under the repurchase program and the other risks detailed from time to time in the Company’s filings with the Securities and Exchange Commission (“SEC”), including but not limited to, its annual report on Form 10-K filed with the SEC on March 3, 2014, and subsequent SEC filings. You are cautioned not to place undue reliance on these forward-looking statements. General Cable does not undertake, and hereby disclaims, any obligation, unless required to do so by applicable securities laws, to update any forward-looking statements as a result of new information, future events or other factors.

Contacts

General Cable Corporation

Len Texter, Vice President, Investor Relations, 859-572-8684









Permalink: http://me-newswire.net/news/10472/en

Heritage Global Partners and Cloud Investment Partners to Manage the Sale of Lufthansa Technik Airmotive Ireland (LTAI) Dublin Plant Assets

LTAI Selects HGP and Cloud to Conduct the Sale on behalf of E-Auctions

SAN DIEGO & DUBLIN - Saturday, March 29th 2014 [ME NewsWire]

Global Online Auction Runs April 30 to May 1

(BUSINESS WIRE) Heritage Global Partners (“HGP”), a global leader in asset advisory and auction services and a subsidiary of Heritage Global Inc. (OTCQB: HGBL), today announced that it is collaborating with Cloud Investment Partners, a global organization with expertise in the aerospace industry, to manage a global online sale featuring the entire assets of the Lufthansa Technik Airmotive (LTAI) Plant in Dublin, Ireland. Per the instruction of LTAI, HGP and Cloud are conducting the sale on behalf of Irish based Auctioneering Company, E-Auctions. LTAI refurbished jet aircraft engines at this location.

Lufthansa Technik Airmotive Ireland Auction April 30, 2014 (9 am GMT) – May 1 (5 pm GMT) Sale Preview: April 29 (LTAI Plant – Naas Road, Rathcoole, Co. Dublin, Ireland) 9 am – 4 pm (local time)

Key Assets Include:

    Huge Inventory of LLP, Non LLP, and Expendable Engine parts
    Engine Test Cell with Tooling, Bellmouths, Fixtures, etc.
    Complete Tooling sets for CFM56-3 & JT9D
    Complete Machine Shops
    Generators
    Borers
    Milling Machines
    Schenk Balancing Machines
    Steel Framed Portable Building
    Relocatable Office/Canteen Buildings
    IT Equipment
    Office Furnishings

“Our sale of LTAI’s assets features a wide range of engineering, inspection, test equipment, works transport, and many more items ideal for organizations in aerospace or other manufacturing industries. We are also selling assets that can be utilized by any number of companies or individual buyers including furniture and IT equipment,” stated Ross Dove, Managing Director, Heritage Global Partners.

David Weiss, Partner of Cloud Investment Partners, stated, “Heritage and Cloud Investment Partners successfully sold other Engine MRO assets including AVEOS and LTQ (Lufthansa Qantas JV) in the last 18 months. We are pleased to have the opportunity to maximize the value of Lufthansa’s Irish Facility assets.”

Heritage Global Partners is one of the leading worldwide asset advisory and auction services firms. HGP specializes in asset brokerage, inspection, and valuations, industrial equipment and real estate auctions, and much more.


Contacts
Chris Matthews, +44 753 845 9839
cmatthews@hgpauction.com

David Weiss, 561-266-0845 x119
david.weiss@cloudlllp.com

Kieron Gammell, +353 45 883 554
kgammell@e-auctions.ie

Rob Rinderman, 212-835-8500
HGP@jcir.com









Permalink: http://www.me-newswire.net/news/10473/en

Polaris Takes Camp RZR to the United Arab Emirates

MINNEAPOLIS - Saturday, March 29th 2014 [ME NewsWire]

(BUSINESS WIRE) Polaris® Industries Inc., (NYSE: PII), the leading manufacturer of off-road vehicles, is showing off its RZR vehicles in the United Arab Emirates. Camp RZR UAE takes place March 28 through March 29, 2014 in Dubai, UAE. The United Arab Emirates is home to some of the world’s best sand dunes, making it the perfect place to hold the event outside of North America.

Polaris is bringing engineers, Jagged X race team and XP1K riding star, RJ Anderson, to meet and ride with UAE off-roaders. The event features riding activities, engineering displays, giveaways, food, music and more. Camp RZR UAE is modeled after the popular U.S. Camp RZR event that takes place annually in Glamis, CA. Each year, more than 20,000 riders travel to the Imperial Sand Dunes Recreation Area to attend.

“Camp RZR UAE is a celebration of off-road riding,” says Craig Scanlon, general manager of the Polaris RZR Division. “Polaris RZR is truly a global brand and we’re excited to bring our premier RZR event to the UAE given their vast interest and passion for the brand.”

More information can be found at http://polaris.nomaduae.com. Follow the event via social media at:

https://www.facebook.com/PolarisRZR
                     

https://www.facebook.com/DubaiRZR

http://instagram.com/dubairzrteam
                     
                       

About Polaris

Polaris is a recognized leader in the powersports industry with annual 2013 sales of $3.8 billion. Polaris designs, engineers, manufactures and markets innovative, high quality off- road vehicles, including all-terrain vehicles (ATVs) and the Polaris RANGER® and RZR® side-by-side vehicles, snowmobiles, motorcycles and on-road electric/hybrid powered vehicles.

Polaris is among the global sales leaders for both snowmobiles and off-road vehicles and has established a presence in the heavyweight cruiser and touring motorcycle market with the Victory and Indian Motorcycle brands. Additionally, Polaris continues to invest in the global on-road small electric/hybrid powered vehicle industry with Global Electric Motorcars (GEM), Goupil Industrie SA, Aixam Mega S.A.S., and internally developed vehicles. Polaris enhances the riding experience with a complete line of Polaris Engineered parts, accessories and apparel and Klim branded apparel.

Polaris Industries Inc. trades on the New York Stock Exchange under the symbol “PII”, and the Company is included in the S&P Mid-Cap 400 stock price index.

Information about the complete line of Polaris products, apparel and vehicle accessories are available from authorized Polaris dealers or anytime at www.polaris.com.

Contacts

Polaris Industries
Donna Beadle, 763-542-2314
donna.beadle@polaris.com









Permalink: http://www.me-newswire.net/news/10483/en

Wolters Kluwer Health Unveils Enhanced UpToDate Android App for Users Worldwide

WALTHAM, Mass. - Wednesday, March 26th 2014 [ME NewsWire]

(BUSINESS WIRE) Wolters Kluwer Health, a leading global provider of information for healthcare professionals and students, announced today the release of significant enhancements to its UpToDate® App for the Android™ mobile platform. The new release delivers an upgraded experience for users worldwide who access the evidence-based clinical decision support resource via the award-winning UpToDate mobile app on their Android smartphones and tablets.

The Android App release delivers richer content, with access to a wide range of UpToDate videos, as well as streamlined searching using “Find in Topic” and filtering options to quickly find topics through bookmarks and history. It also offers faster automatic content updates over Wi-Fi for UpToDate MobileComplete™, which provides users with full access to UpToDate even without a network connection.

Of particular interest to global Android users is the addition of Search in Your Own Language, a customizable suite of search and navigation tools that enables them to research clinical questions in their native language. This unique feature streamlines searches for clinical information and graded recommendations by leveraging an advanced, patent-pending translation system for search terms in Simplified and Traditional Chinese, French, German, Italian, Portuguese, Spanish, Japanese and English. An intuitive auto-complete feature also predicts words or phrases in a clinician’s native language.

“Clinicians worldwide rely on UpToDate to quickly provide answers to clinical questions at the point of care, and a rapidly growing number are doing so with Android smartphones and tablets,” said Denise Basow, MD, Vice President/General Manager, UpToDate at Wolters Kluwer Health, Clinical Solutions.

According to Gartner, the Android operating system continues to dominate the global marketplace with a 78.4% share of the smartphone market. Dr. Basow adds: “Low-cost Android devices, for example, help enable mobile access to UpToDate for clinicians in resource-limited regions worldwide. Our mission is to improve healthcare, everywhere, and our recent Android enhancements demonstrate our commitment to providing Android users with easy access to the clinical answers they need, when and where they need them.”

The new UpToDate for Android app release is available free on Google Play, https://play.google.com/store/apps/details?id=com.uptodate.android and on the Amazon Appstore for Android, http://amzn.com/B00A4LX7R8. (Subscription required.)

Follow UpToDate on Facebook, Twitter and LinkedIn.

About Wolters Kluwer Health

Wolters Kluwer Health is a leading global provider of information, business intelligence and point-of-care solutions for the healthcare industry. Serving more than 150 countries and territories worldwide, Wolters Kluwer Health’s customers include professionals, institutions and students in medicine, nursing, allied health and pharmacy. Major brands includeHealth Language®, Lexicomp®, Lippincott Williams & Wilkins, Medicom®, Medknow, Ovid®, Pharmacy OneSource®, ProVation® Medical and UpToDate®.

Wolters Kluwer Health is part of Wolters Kluwer, a market-leading global information services company. Wolters Kluwer had 2012 annual revenues of €3.6 billion ($4.6 billion), employs approximately 19,000 people worldwide, and maintains operations in over 40 countries across Europe, North America, Asia Pacific, and Latin America. Follow our official Twitter handle: @WKHealth.

Android and Google Play are trademarks of Google Inc.

Contacts

Wolters Kluwer Health | UpToDate

André Rebelo, +1 781-392-2411

Public & Analyst Relations Manager

andre.rebelo@wolterskluwer.com









Permalink: http://me-newswire.net/news/10456/en

Nature Genetics Founding Editor Kevin Davies Joins Pathway Genomics’ Scientific Advisory Board

ME Newswire / Business Wire

SAN DIEGO. - Friday, March 28th 2014

Pathway Genomics Corporation, a San Diego-based CLIA and CAP accredited clinical laboratory that offers genetic testing services globally, announced that Nature Genetics founding editor Kevin Davies, Ph.D., has joined its scientific advisory board.

“I have followed Pathway closely for many years, reporting on the launch of the company in my book, The $1,000 Genome,” said Davies. “I believe Pathway is poised to make a major contribution to clinical diagnostics and improving the wellness of millions of patients. I hope to make a modest contribution to that effort.”

A highly respected science journalist, editor, and publisher with more than 20 years of experience at the forefront of advances in genetics and medicine, Davies is currently a vice president with the American Chemical Society, the largest scientific society in the world, where he serves as publisher of Chemical & Engineering News, the society’s weekly magazine. He has also served as editor-in-chief for Cell Press and was the founding editor of Bio-IT World magazine.

“Kevin is a vital thought leader in the genomics space and his work is a significant contribution to progress in the field,” said Ardy Arianpour, Pathway Genomics’ chief strategy officer. “We are exceptionally pleased to collaborate with an opinion leader of his status.”

Born in London, Davies studied biochemistry and molecular genetics at the Universities of Oxford and London before moving to the United States. He conducted postdoctoral fellowships at MIT and Harvard Medical School before moving into science publishing. Davies is the author of three popular-science books on the medical and societal implications of the genomics revolution, including Cracking the Genomeand most recently The $1,000 Genome. He is a sought-after public speaker and an occasional technical consultant to the film industry, most recently serving as genetics consultant for the film Decoding Annie Parker.

Pathway Genomics’ scientific advisory board consists of leaders in various fields including oncology, pharmacogenomics, endocrinology, bioinformatics, biostatistics, behavioral genetics, nutrigenomics, and human epigenetics. To view the company’s full scientific advisory board, visit www.pathway.com.

About Pathway Genomics Corporation

As a CLIA and CAP accredited clinical laboratory based in San Diego, California, Pathway Genomics provides physicians and their patients with actionable and accurate genetic information to improve or maintain health and wellness. Since its founding in 2008, Pathway Genomics has become known for its dedication to innovation and commitment to medical responsibility – making it a leader in the commercial genetic testing industry. Pathway Genomics’ testing services cover a variety of conditions including cardiac health, cancer risk, inherited diseases, nutrition and exercise response, as well as drug response for specific medications including those used in pain management and mental health. For more about Pathway Genomics, visit www.pathway.com.

Contacts

Pathway Genomics Corporation

Zak Pugh, 858-217-4358

pr@pathway.com

www.pathway.com









Permalink: http://me-newswire.net/news/10471/en

Friday, March 28, 2014

Quintiles Appoints Dr. Stella Blackburn to Lead Global Risk Management for Real-World & Late Phase Research

Industry Expert Previously Served as Risk Management Development and Scientific Lead at the European Medicines Agency (EMA)

RESEARCH TRIANGLE PARK, N.C. - Friday, March 28th 2014 [ME NewsWire]

(BUSINESS WIRE) Quintiles today announced that Stella Blackburn, M.B. B.S., has been appointed as the vice president and global head of Risk Management for its Real-World & Late Phase Research group. In this role, Dr. Blackburn will be responsible for leading the group’s risk management efforts in North America, EU and Asia-Pacific. Dr. Blackburn also will develop multidisciplinary benefit risk management services, review and assist customers with interpretation of pharmacovigilance legislation, and ensure compliance with regulations and best practices in the conduct of pharmacovigilance and risk management activities for the company’s real-world and late phase research efforts.

With more than two decades of experience in the pharmacovigilance and pharmacoepidemiology fields, Dr. Blackburn joins Quintiles from the European Medicines Agency (EMA) where she served for more than 16 years in various roles, most recently as the EMA Risk Management Development and Scientific Lead. In this role, Dr. Blackburn was responsible for designing and implementing risk management public policy and processes used throughout Europe. Dr. Blackburn also worked with biopharmaceutical companies, government bodies and industry consortia to advance risk management and real-world research, including registry projects and public-private partnerships.

“Stella’s experience developing innovative risk management solutions for our customers is a tremendous addition to our team,” said Cynthia Verst, M.S., Pharm.D., president, Real-World & Late Phase Research at Quintiles. “Throughout her career, Stella has forged cross-sector partnerships — driving the sort of collaboration we are cultivating here at Quintiles — to develop comprehensive risk management policies and processes designed to protect patients and advance clinical research worldwide. She brings a range of unique safety expertise and experience that we can leverage across our business to better assist our customers with solutions to meet regulatory and reimbursement requirements for their products, and subsequent risk benefit monitoring.”

“I am very excited to be joining Quintiles to lead the global risk management efforts for the company’s Real-World & Late Phase Research group,” said Dr. Blackburn. “Together with my colleagues at Quintiles, I aim to provide best-in-class solutions for real-world and late phase evidence development across the global healthcare system and to further develop risk management practices to benefit patients throughout the world.”

Before joining the EMA, Dr. Blackburn worked in hospital medicine and also spent more than 11 years in the pharmaceutical industry in a variety of leadership roles. Throughout her career, Dr. Blackburn has lectured around the world on pharmacovigilance and risk management and written chapters on the same topic in several textbooks and industry-related guides. Dr. Blackburn is also the past-President of the International Society of Pharmacoepidemiology. Dr. Blackburn trained in medicine at the University of Cambridge and the University of London Guy’s Hospital Medical School. She earned her Master of Science in Epidemiology from the London School of Hygiene and Tropical Medicine.

She is a Fellow of the Royal College of Physicians of Edinburgh, the International Society of Pharmacoepidemiology and the Faculty of Pharmaceutical Medicine of the Royal Colleges of Physicians in the UK.

About Quintiles

Quintiles (NYSE: Q) is the world’s largest provider of biopharmaceutical development and commercial outsourcing services with a network of more than 28,000 employees conducting business in approximately 100 countries. We have helped develop or commercialize all of the top-50 best-selling drugs on the market. Quintiles applies the breadth and depth of our service offerings along with extensive therapeutic, scientific and analytics expertise to help our customers navigate an increasingly complex healthcare environment as they seek to improve efficiency and effectiveness in the delivery of better healthcare outcomes. To learn more about Quintiles, please visit www.quintiles.com.

Click here to subscribe to Mobile Alerts for Quintiles.

Contacts

Quintiles

Mari Mansfield, Media Relations

+ 1.919.998.2639 (office), +1.919.259.3298 (mobile)

mari.mansfield@quintiles.com



Karl Deonanan, Investor Relations

+1.919.998.2789

InvestorRelations@quintiles.com







Permalink: http://www.me-newswire.net/news/10470/en

Thursday, March 27, 2014

Toshiba Launches VGA CMOS Image Sensors for Surveillance Cameras and Drive Recorders

Enables High Sensitivity Video Capturing under Low Light Conditions

TOKYO. - Thursday, March 27th 2014 [ME NewsWire]

(BUSINESS WIRE) Toshiba Corporation (TOKYO:6502) announced today that it will start mass production shipments of “TCM3211PB”, a 1/4 inch VGA CMOS area image sensor for surveillance cameras and drive recorders, at the end of April. The new sensor adopts large 5.6 µm pixels, improving low light sensitivity. Even in moonlight1, bright images can be captured. The sensor also incorporates a single frame HDR (High Dynamic Range) function2 based on Toshiba algorithm. It reduces false color3 and faithfully reproduces dark and bright areas in high contrast images. The product’s high frame rate of 60 fps at full resolution enables smooth and seamless capture of video images.

Applications

    Cameras for security, surveillance and drive recorder applications

Key Features

    High sensitivity achieved by 5.6 μm pixels.
    HDR function realizes high dynamic range of 108dB.
    Adoption of PBGA (Plastic Ball Grid Array) package contributes to downsizing of camera systems.



Main Specifications

Product Name
         

TCM3211PB

Resolution
         

VGA

Optical Format
         

1/4 inch

Aspect Ratio
         

4:3

Pixel Pitch
         

5.6 μm

Full Size Frame Rate
         

60 fps


Notes: 1. Equivalent to about 0.2 lux. 2. A method for simultaneously applying different exposure times to each line of an image and composing them into a single image. For further information about the detail of single frame HDR, please visit. http://www.semicon.toshiba.co.jp/eng/product/sensor/cmos/hdr/index.html#singleflame 3. The phenomenon of sensors producing false colors not true to the imaged objects.

For further information about these products, please visit. http://www.semicon.toshiba.co.jp/info/lookup.jsp?pid=TCM3211PB&lang=en

Customer inquiries Image Sensor Sales & Marketing Department Tel : +81-3-3457-3370

Information in this document, including product prices and specifications, content of services and contact information, is current on the date of the announcement but is subject to change without prior notice.

About Toshiba

Toshiba is a world-leading diversified manufacturer, solutions provider and marketer of advanced electronic and electrical products and systems. Toshiba Group brings innovation and imagination to a wide range of businesses: digital products, including LCD TVs, notebook PCs, retail solutions and MFPs; electronic devices, including semiconductors, storage products and materials; industrial and social infrastructure systems, including power generation systems, smart community solutions, medical systems and escalators & elevators; and home appliances.

Toshiba was founded in 1875, and today operates a global network of more than 590 consolidated companies, with 206,000 employees worldwide and annual sales surpassing 5.8 trillion yen (US$61 billion). Visit Toshiba's web site at www.toshiba.co.jp/index.htm

Photos/Multimedia Gallery Available: http://www.businesswire.com/cgi-bin/mmg.cgi?eid=50832815&lang=en

Contacts

Media Inquiries:

Toshiba Corporation

Semiconductor & Storage Products Company

Takashi Mochizuki, +81-3-3457-4963

semicon-NR-mailbox@ml.toshiba.co.jp









Permalink: http://me-newswire.net/news/10461/en

Quintiles Announces Exercise of the Underwriters' Option to Purchase Additional Secondary Shares

RESEARCH TRIANGLE PARK, N.C. - Thursday, March 27th 2014 [ME NewsWire]

(BUSINESS WIRE) Quintiles today announced that the underwriters of the previously announced secondary public offering of 15 million shares of its common stock have exercised in full their option to purchase an additional 2.25 million shares from certain shareholders of Quintiles. After giving effect to the sale of the additional shares, which was completed on March 26, 2014, the selling shareholders sold a total of 17,250,000 shares of Quintiles’ common stock in the offering at a price to the public of $52.00 per share.

Quintiles did not sell any shares in this offering, including the shares subject to the option to purchase additional shares, and did not receive any proceeds from the sale of the shares.

Morgan Stanley, Barclays and J.P. Morgan served as joint book-running managers and as representatives of the underwriters for the offering. Citigroup, Goldman, Sachs & Co., Wells Fargo Securities, BofA Merrill Lynch and Deutsche Bank Securities served as book-running managers for the offering. Baird, William Blair and Jefferies served as lead co-managers, and Guggenheim Securities, Piper Jaffray, Raymond James, RBC Capital Markets and UBS Investment Bank served as co-managers for the offering.

A registration statement relating to these securities was declared effective by the Securities and Exchange Commission on March 12, 2014. The offering was made only by means of a prospectus. Copies of the final prospectus relating to the offering may be obtained from: Morgan Stanley & Co. LLC, Attention: Prospectus Department, 180 Varick Street, 2nd Floor, New York, NY 10014, via telephone: +1 (866) 718-1649 or by email: prospectus@morganstanley.com; Barclays Capital Inc. c/o Broadridge Financial Solutions, 1155 Long Island Avenue, Edgewood, NY 11717 via telephone: +1 (888) 603-5847, or by email: barclaysprospectus@broadridge.com; J.P. Morgan Securities LLC, Attention: Broadridge Financial Solutions, 1155 Long Island Avenue, Edgewood, NY 11717 or via telephone: +1 (866) 803-9204.

This press release shall not constitute an offer to sell or the solicitation of an offer to buy, nor shall there be any sale of these securities in any state or other jurisdiction in which such an offer, solicitation or sale would be unlawful prior to registration or qualification under the securities laws of any such state or other jurisdiction.

About Quintiles

Quintiles (NYSE: Q) is the world’s largest provider of biopharmaceutical development and commercial outsourcing services with a network of more than 28,000 employees conducting business in approximately 100 countries. We have helped develop or commercialize all of the top-50 best-selling drugs on the market. Quintiles applies the breadth and depth of our service offerings along with extensive therapeutic, scientific and analytics expertise to help our customers navigate an increasingly complex healthcare environment as they seek to improve efficiency and effectiveness in the delivery of better healthcare outcomes.

Contacts

Quintiles

Phil Bridges, Media Relations (phil.bridges@quintiles.com)

+1-919-998-1653 (office) +1-919-457-6347 (mobile)



Karl Deonanan, Investor Relations (InvestorRelations@quintiles.com)

+1-919-998-2789

Permalink: http://me-newswire.net/news/10460/en

OT and Network International Announce Strategic Partnership on Banking Cards and Personalisation & Celebrate the Inauguration of OT’s Largest Service Centre in the MEA Region

COLOMBES, France. - Wednesday, March 26th 2014 [ME NewsWire]

(BUSINESS WIRE) Oberthur Technologies (OT), a world leader in digital security solutions for the mobility space and Network International, the leading payment solutions provider in the Middle East, today announced a strategic partnership which brings together a complete portfolio of payment solutions including card personalisation, EMV and related payment security services to clients across the Middle East and Africa. OT is also pleased to announce the inauguration of the largest service centre within the MEA region, located in Dubai.

The partnership leverages on OT’s expertise in the smartcard industry and on its Common Personalisation System (CPS). With the opening of its state of the art service centre located in Dubai, OT will provide personalisation and fulfilment services to its customers across Middle East and Africa. It is fully certified by both MasterCard and Visa, measures 800 m² and has a capacity to issue 15Mu cards annually.The new service centre consolidates OT’s acquisition of Cupola Plastic Cards in 2012 and Obernet in 2013 to create a centre of excellence in this region.

Network International’s strong customer base and relationships across the Middle East make them an ideal partner for OT, in order to introduce advanced solutions in personalisation, mobile payments, NFC and authentication. Their decision to use OT’s technologies is proof of how the company is transforming itself to accelerate its development and capture new market opportunities.

“We are pleased to announce this partnership with Network International which has certainly played a vital role in transforming the UAE’s payment service industry. The continued cooperation between both companies and especially this new agreement enables us to increase the scale of our local business and offer an array of new valuable services in the country” said Eric Duforest, Managing Director of the Payment Business Unit at OT. “We are also pleased to have inaugurated our service centre in Dubai, which is the largest in the MEA region.”

Bhairav Trivedi, Chief Executive Officer, Network International, said: “With cards becoming an object of prestige and value beyond their payment capability, card personalization is becoming increasingly important today. Financial institutions view their payment cards as primary drivers in strengthening cardholder relationships, and are often on the lookout for innovation and security focused features that can add considerable value. Network International is confident that this partnership with OT will enable us to offer clients tailored solutions that will exceed their expectations.”

ABOUT OBERTHUR TECHNOLOGIES

OT is a world leader in digital security solutions for the mobility space. OT has always been at the heart of mobility, from the first smart cards to the latest contactless payment technologies which equip millions of smartphones. Present in the Payment, Telecommunications and Identity markets, OT offers end-to-end solutions in the Smart Transactions, Mobile Financial Services, Machine-to-Machine, Digital Identity and Transport & Access Control fields. OT employs over 6 000 employees worldwide, including 600 R&D people. With more than 50 sales offices across 5 continents and 10 facilities, OT’s international network serves clients in 140 countries. For more information: www.oberthur.com

ABOUT NETWORK INTERNATIONAL

Established in 1994, Network International LLC is the largest acquirer, and one of the leading payment solutions providers in the Middle East, geared to meet the needs of banks, financial institutions and large and individual retailers. It is a Principal Member of Visa International and MasterCard International for the UAE, offering customers the most comprehensive range of payment products and services for both the Issuing and Acquiring segment of the card payment industry. Offerings include credit and debit card processing services, ATM management and monitoring, merchant acquiring plus consumer finance applications. Network International provides consultancy services ranging from planning and designing, to developing of new card and consumer finance products and services.

Network International is the first independent vendor certified by both Visa & MasterCard for card payments in the Middle East. It is the UAE's largest payment acquirer for Credit & Debit Cards and the largest third-party processing vendor offering complete EMV certified solutions as institutions migrate to EMV Smart Card technology.

Contacts

MEDIA CONTACTS
Oberthur Technologies
Audrey Besnardeau, Tel : +33 1 78 14 76 75
a.besnardeau@oberthur.com



FTI Consulting Strategic Communication
Yannick Duvergé, Tel : +33 1 47 03 68 65 / +33 6 74 91 48 05
yannick.duverge@fticonsulting.com







Permalink: http://www.me-newswire.net/news/10452/en

Wednesday, March 26, 2014

ZTE Posts Profit of RMB 1.36 Billion as 4G Strength Leads Recovery

ME Newswire / Business Wire

Strong improvement in gross margin in carrier network operations as ZTE focuses on innovation to capitalize on acceleration in global 4G deployments

SHENZHEN, China. - Thursday, March 27th 2014

ZTE Corporation (“ZTE”) (H share stock code: 0763.HK / A share stock code: 000063.SZ), a publicly-listed global provider of telecommunications equipment, network solutions and mobile devices, reported a full-year profit in 2013 as the company sharpened its focus on key operations such as 4G, while strengthening operational management to generate cost savings and efficiencies.

Net profit attributable to shareholders of the listed company was RMB 1.36 billion in 2013, or RMB 0.39 per share, compared with a loss a year earlier. The company declared a cash dividend of RMB 0.3 (including taxation) for every 10 shares held, representing 75.8% of total net profit of the year available for distribution. Revenue fell 10.6% to RMB75.2 billion.

Please download infographic for pictorial representation of ZTE’s business performance in 2013: http://wwwen.zte.com.cn/en/products/bearer/201403/P020140326691257063470.png

Fastest-growing 4G solutions provider in 2013

In 2013, ZTE prioritized on strategically important operations in populous countries, and the development of business with major international operators. The company exercised stringent control over contracts with lower margins, resulting in improved gross margin for international projects. In China, ZTE secured market-leading positions in 4G network tenders, as the company benefited from the development of proprietary technology solutions such as Cloud Radio. Internationally, the company’s 4G business accelerated.

ZTE was the world’s fastest-growing provider of 4G solutions in 2013, according to research company IHS.

ZTE reported operating revenue of RMB35.63 billion from the mainland China market, accounting for 47.4% of the company’s overall operating revenue. Apart from the rapid development of the 4G business, ZTE also targeted strategically important opportunities such as “Smart City” metropolitan information systems, cloud computing and the Internet of Things.

The company reported operating revenue of RMB39.60 billion from international operations, accounting for 52.6% of overall operating revenue. As a result of efforts to focus on major countries and mainstream operator partners, ZTE strengthened its relationships with key multinational customers.

Aside from the acceleration in the company’s 4G business, ZTE’s wireless products division continues to target opportunities in network expansion and upgrade in 2G and 3G networks. The company is also actively engaged in the research, development and planning of 5G and other next-generation technologies.

In connection with wireline and optical communications products, the company reported relatively fast growth in operating revenue from wireline switch and access products on the back of ongoing investment in research and development and outstanding product competitiveness, while such growth was also being driven by the rapid development of the broadband market and the construction of supporting facilities for the Mobile Internet.

In terms of the service products, the company achieved new breakthroughs in IPTV and video conference products with Tier-1 international operators, resulting in enhanced global market share for the company.

In 2013, operating revenue from terminal products decreased as a result of lower demand for feature phones and data cards. Smartphones and other smart terminal products now contribute a bigger percentage of total revenue, driven by the rapid development of the Mobile Internet. The company will be committed to enhancing the competitiveness of its terminal products, adopting a more consumer-centric approach together with online-based business model. While maintaining and enhancing ZTE’s competitive edge in hardware, the company will also be focused on developing software and services to provide improved user experience to consumers through innovation.

Leading the next phase of ICT development

Looking ahead to 2014, opportunities as well as challenges will abound in the telecommunications industry amid the full-fledged application of 4G technologies, the amalgamation of ICT industries and continued informatisation. In connection with carriers’ networks, the full-scale roll-out of 4G network deployment over the world, especially the large-scale construction of 4G networks in China, is set to usher in surging new developments for the telecommunications industry, although 3G/4G/WLAN technologies will continue to coexist. Broadband infrastructure plans by national governments, users’ demand and technology upgrades will drive the construction of global broadband networks, while the building of transmission networks that support wireless or wireline broadband will also continue.

This month, ZTE retained its top-2 ranking in the World Intellectual Property Organization’s latest annual table of patent applicants, strengthening the company’s position as one of the world’s leading technology innovators. ZTE ranked No. 1 in both 2011 and 2012, according to WIPO. ZTE has filed applications for more than 50,000 patents globally, with more than 16,000 granted, and is a global leader with more than 800 ETSI essential patents on the standardization 4G LTE. ZTE is committing large resources to the development of 5G technologies, leveraging the company’s position of strength in 4G.

Regarding smart terminals, next generation products will feature higher levels of intelligence affording greater flexibility to users. Wearable device will present a new direction of development, as the fulfillment of consumers’ needs becomes a crucial determining factor. In the government and enterprise service sectors, areas of keen market interest, such as industry informatisation, the Internet of Things, Cloud Computing, the Smart City and information security, etc, are set to present business opportunities to the Group.

In 2014, ZTE will continue to channel resources to accelerate business development in areas representing the highest strategic importance and greatest opportunity for the company. ZTE will combine technology innovation with strong strategic and business execution as the company continues to satisfy customers’ needs and pursue strong returns for shareholders.

About ZTE

ZTE is a publicly-listed global provider of telecommunications equipment and network solutions with the most comprehensive product range covering virtually every telecommunications sector, including wireless, access & bearer, VAS, terminals and professional services. The company delivers innovative, custom-made products and services to over 500 operators in more than 160 countries, helping them to meet the changing needs of their customers while growing revenue. ZTE commits 10 per cent of its annual revenue to research and development and has leadership roles in several international bodies devoted to developing telecommunications industry standards. ZTE is committed to corporate social responsibility and is a member of the UN Global Compact. The company is China’s only listed telecom manufacturer that is publicly traded on both the Hong Kong and Shenzhen Stock Exchanges (H share stock code: 0763.HK / A share stock code: 000063.SZ). For more information, please visit www.zte.com.cn.

Contacts

ZTE Corporation

Margrete Ma, +86 755 26775207

ma.gaili@zte.com.cn



Edelman PR

Mark Lee / Andres Vejarano

Tel: +852 2837 4756 / 2837 4735

mark.lee@edelman.com

andres.vejarano@edelman.com







Permalink: http://me-newswire.net/news/10457/en

David Knights Joins Investors Trust Assurance SPC

GRAND CAYMAN, Cayman Islands - Wednesday, March 26th 2014 [ME NewsWire]

(BUSINESS WIRE)We are pleased to announce that David Knights has joined Investors Trust Assurance SPC (“ITA”) as Head of Asia Distribution. With over 25 years of experience within the financial services industry, David began his career at Eagle Star Insurance in the UK in 1988 and then worked for Provident Mutual Assurance, also in the UK covering business development roles at both companies. In 1995, he joined Friends Provident International as a member of the sales team and, over a period of 19 years, he held a number of sales and business development roles covering various international markets including Regional Sales Director, North Asia and more recently General Manager of FPI’s Hong Kong business.

Based in Hong Kong, Knights’ key role will be business development in Asia, building on ITA’s existing distribution in the region with particular emphasis on developing distribution in the offshore expatriate market. He will also be assuming responsibility for the leadership of ITA’s Asia sales team.

Upon his appointment, Knights commented, "I am really excited to be joining ITA and supporting their growth plans for Asia and in particular development of the offshore expatriate market in the region. I have spent most of my 25 years in Financial Services focusing on distribution, and I am passionate about delivering great service and support to advisers and their clients. I was strongly attracted by ITA’s clear strategy for sustainable growth supported by a cutting edge technology platform, which delivers a superb user experience combined with an attractive product range. Joining as I do, when ITA is expanding their product offering further, I believe we have a terrific proposition to share with advisers in the region.”

Bob Pain, ITA’s Managing Director, commented on Knights’ appointment, “I am delighted David has joined us at this exciting time for Investors Trust. He has done a superb job at FPI over many years, and we are confident he will add value to our business in Asia through his leadership, experience and passion. We wish him every success in his career with us and look forward to him continuing to build ITA’s reputation and brand in the region.”

Contacts

Investors Trust Assurance SPC

Allison Clark, 345-749-3342

Compliance Officer









Permalink: http://www.me-newswire.net/news/10433/en

Okinawa Prefecture and Changi Airport Partner to Enhance Travel Capabilities

Memorandum of Understanding set to expand aviation network between Singapore and Okinawa

NAHA, Japan - Wednesday, March 26th 2014 [ME NewsWire]

(BUSINESS WIRE)-- The Governor of Okinawa Prefectural Government, Mr. Hirokazu Nakaima and Changi Airport Senior Advisor, Mr. Wong Woon Liong, today signed a memorandum of understanding (MOU) to strengthen the aviation network between Okinawa and Singapore. Under the MOU, Okinawa and the Changi Airport have agreed to work closely to promote tourism and trade exchange between Okinawa, Singapore, South East Asia and beyond markets including India and Australia.

Some initiatives in the pipeline will include working with airlines to create new routes from the two cities and promoting direct flights to increase the numbers of visitors from Singapore and other regions.

Regional promotion to 1.2 billion residents of South East and South Asian countries including Malaysia, Indonesia, Australia, India and other regions will aim to promote Singapore as a travel hub to Okinawa.

Trade will also receive a boost with Okinawa aiming to work with enterprises with access to international air cargo logistics, to grow distribution channels for Okinawan products to Singapore and neighboring markets. Okinawa is a robust exporter of healthy and high quality food including fresh produce, brown sugar lump, salt and sweet goods. These are well reputed among overseas countries.

“It is a great honor for me to be here for the signing of the MOU between Singapore Changi Airport and Okinawa Prefecture. This MOU is aimed at enhancing direct air connectivity between the two cities. Changi Airport is keen to establish a direct link to Okinawa. The prefecture shares the common interest to promote tourism, trade and transport people from one destination to another,” said Mr. Wong Woon Liong.

“With this non-stop flight inauguration, it will decrease flight time to Okinawa, and provide greater comfort and convenience to business and leisure travelers. To start with, we will work together with key travel agencies to launch charter flights between Singapore and Okinawa. This will create and further develop the Singapore-Okinawa market for the first scheduled direct flights. We are also planning to conduct marketing promotion activities together,” he added.

“It is a great honor for us to have a signing ceremony with the presence of Mr. Wong Woon Liong, as a representative from Changi Airport, and many other respectful guests around the world. As everybody knows, Changi Airport is one of the world’s leading airports and a hub for 1.2 billion residents in the South East and South Asian region. Through this relationship, we expect our prefecture’s aviation network to be further strengthened to increase tourism and air cargo,” said Governor Hirokazu Nakaima.

“We also expect that Okinawa will be widely known as a new, attractive destination in Japan through our ongoing and future promotions in Singapore and many other regions,” he added.

The signing ceremony was held today at the international terminal of Naha Airport.

About Changi Airport

Changi Airport (www.changiairport.com) is the world’s most awarded airport with more than 450 accolades received since it opened in 1981. To serve passengers and visitors from the world over, there are over 350 retail stores and 120 F&B outlets across the airport's three terminals. Changi handled more than 53 million passenger movements in 2013, an annual record. Today, it serves more than 100 airlines flying to 280 cities in about 60 countries and territories worldwide. A flight takes off or lands at Changi roughly once every 90 seconds.

About Okinawa Prefecture

Okinawa Prefecture, located in the southernmost part of Japan, consists of more than 160 large or small beautiful islands, scattered in the vast ocean. Okinawa, with its warm climate in the subtropical-oceanic zone, has a diversity of ecosystems and is a habitat for a variety of animals and plants including beautiful corals. Since Okinawa has a long history with the Asian continent for overseas commerce, a unique history and culture has developed. Such uniqueness is seen in the archaeological digs, architecture, arts and crafts, entertainment, cuisine and customs.

Okinawa recently conducted tourism and trade promotion in 15 global markets based on detailed survey results.

Okinawa’s tourism website is available in 10 languages including Japanese, English, Chinese, Korean, Russian, German, Spanish and Portuguese. Okinawa accommodates overseas travelers with its hospitality and tradition. For more information, please visit http://www.okinawastory.jp/en/

Photos/Multimedia Gallery Available: http://www.businesswire.com/cgi-bin/mmg.cgi?eid=50830163&lang=en

Contacts

Okinawa Prefectural Government

Ken Yamashiro, +81 98 866 2764

Tourism Promotion Division

yamashkn@pref.okinawa.lg.jp









Permalink: http://me-newswire.net/news/10447/en

Toshiba Launches Interface Bridge ICs That Support Next Generation Content Security Technology, SeeQVault™

Supports SeeQVault™-Enabled USB Storages

TOKYO - Wednesday, March 26th 2014 [ME NewsWire]

(BUSINESS WIRE) Toshiba Corporation (TOKYO: 6502) today announced the launch of “TC358782XBG,” an interface bridge IC that supports SeeQVault™, a next generation security specification that allows copy protected HD content to be transferred to portable storage devices. Sample shipments will start in April, with mass production scheduled to start for August.

Protected HD content is not transferrable to external memories; users need to play the content on the equipment that records it or downconverts it to SD quality. SeeQVault™ provides a solution for compliant equipment, and allows HD content to be viewed on multiple platforms. This is achieved with a secure ID assigned to each SeeQVault™-compliant flash memory, such as SD memory cards.

“TC358782XBG” brings SeeQVault’s™ features to portable storage devices, such as USB HDDs. This allows secure transfers of HD content, and enables users to play HD content on multiple SeeQVault™-compatible equipment.

Applications SeeQVault™-enabled USB storages, such as mobile HDDs and SD card adaptors

To view the main specifications kindly click here

Information in this document, including product prices and specifications, content of services and contact information, is current on the date of the announcement but is subject to change without prior notice.

About Toshiba Toshiba is a world-leading diversified manufacturer, solutions provider and marketer of advanced electronic and electrical products and systems. Toshiba Group brings innovation and imagination to a wide range of businesses: digital products, including LCD TVs, notebook PCs, retail solutions and MFPs; electronic devices, including semiconductors, storage products and materials; industrial and social infrastructure systems, including power generation systems, smart community solutions, medical systems and escalators & elevators; and home appliances.

Toshiba was founded in 1875, and today operates a global network of more than 590 consolidated companies, with 206,000 employees worldwide and annual sales surpassing 5.8 trillion yen (US$61 billion). Visit Toshiba's web site at www.toshiba.co.jp/index.htm.

Photos/Multimedia Gallery Available: http://www.businesswire.com/multimedia/home/20140325006701/en/

To view the full release including the table, please click here

Contacts

Toshiba Corporation

Semiconductor & Storage Products Company

Takashi Mochizuki, +81-3-3457-4963

semicon-NR-mailbox@ml.toshiba.co.jp








Tuesday, March 25, 2014

EnVerv Announces Closing of $15.4M Series C Investment Round

New round of financing fuels expansion of current customer base and development of new products

SAN JOSE, Calif - Tuesday, March 25th 2014 [ME NewsWire]

(BUSINESS WIRE)-- EnVerv Inc., an innovative fabless semiconductor company and a leading provider of high performance communications and metering System on Chip (SoC) solutions for the Advanced Metering Infrastructure (AMI), smart grid, solar and other grid connectivity markets, announced today the closing of its $15.4M round of series C financing with participation from Cassiopeia Capital Partners, Cisco, UMC Capital and existing investors Benchmark Capital, NEA and Walden International.

“We are very glad to have raised this sizable round of investment,” said Michael Raam, CEO and President of EnVerv. “This round further underscores our dedication to providing high-performance SoC solutions to our customers. We intend to utilize this capital to support the production ramps, expand our customer base, and also continue the development of new product families in wired and wireless communications as well as metering market segments.”

“Our investment in EnVerv signifies our belief in not only their business model and product offerings but also their execution in combining complex communication algorithms with high levels of integration in offering the lowest power and most cost-effective single chip solutions to their customers,” said Frank Lee of UMC Capital.

About EnVerv Inc.

EnVerv is a fabless semiconductor company in the United States with headquarters in Milpitas, California. The company's SoC solutions enable robust and high-speed communications over Low Voltage (LV) and Medium Voltage (MV) power lines that are applicable to various grid connectivity markets such as AMI, solar micro-inverters, transformer monitoring, substation communications, lighting networks, etc. EnVerv’s family of communications SoC solutions comprises single-chip soft-modems and covers ITU-T G.9903 (G3-PLC), ITU-T (G.9904) PRIME, IEEE 1901.2 and IEC-61334 (S-FSK) standards across CENELEC, FCC and ARIB frequency bands. For more information please visit www.enverv.com.

Contacts

EnVerv

Afshin Shaybani, +1 858.224.0006

afshin.shaybani@enverv.com









Permalink: http://www.me-newswire.net/news/10435/en

FTV Capital Closes Oversubscribed Growth Equity Fund

ME Newswire / Businesswire

FTV IV Surpasses $500 Million Target, Closing on $700 Million in L.P. Commitments

SAN FRANCISCO & NEW YORK. - Tuesday, March 25th 2014

FTV Capital, a sector-focused growth equity investment firm, today announced the final closing of its fourth fund, FTV IV, L.P. (“FTV IV”), with $700 million of limited partner commitments. Formed to continue the successful growth equity strategy of its predecessor fund, FTV IV had an initial target of $500 million and was significantly oversubscribed. FTV Capital has raised over $1.8 billion across four funds since its inception.

FTV will continue its focus on high-growth companies with innovative solutions, established business models and strong management teams that value its collaborative approach to building great companies. FTV invests at the intersection of its core sectors -- enterprise solutions (business services and technology), financial services and payments/transaction processing -- where its market insight, domain expertise, track record and Global Partner Network can add significant value. Often the first institutional investor, FTV target companies have $10 million to $100 million in revenue and are growing 20 percent plus annually, are typically profitable, and are validated by blue chip enterprise customers and distribution partners.

Investors in FTV IV are globally diverse and include banks, insurance companies, public and corporate pension plans, college and university endowments, foundations, investment advisors, family offices, high net worth individuals and strategic investors.

“We are extremely grateful for the support of our existing investors who value our distinct approach to growth equity investing and the strong results we have generated,” said Richard Garman, FTV Capital managing partner. “Our long-tenured team, deep sector knowledge, theme-based sourcing approach and unique Global Partner Network were also appealing to high quality, new investors who have chosen to partner with FTV. We are very excited to welcome our new investors to the fund.”

“Our team has already invested $170 million in five exciting new FTV IV portfolio companies which achieved aggregate revenue growth of 49% in 2013,” said Brad Bernstein, FTV Capital partner and head of the New York office. “The new capital will enable us to continue to partner with proven, motivated management teams in highly attractive businesses, where our contributions can help accelerate revenue growth, profitability and compelling returns for our investors.”

“Given the highly competitive fundraising environment, we were thrilled by the significant demand for FTV IV,” said Karen Derr Gilbert, FTV Capital partner and head of business development who spearheaded FTV’s fundraising efforts. “We are appreciative of the confidence our existing investors continue to entrust us with, and we look forward to building long-term, productive relationships with our new investors.”

Founded in 1998, FTV Capital has invested in 81 portfolio companies and has offices in San Francisco and New York. FTV Capital leverages its industry sector expertise and distinct Global Partner Network, a group of the world’s leading enterprises and executives, to help portfolio companies drive growth. Many successful companies have partnered with FTV including Aveksa (acquired by RSA, the security division of EMC), Castle Pines Capital (acquired by Wells Fargo), Coremetrics (acquired by IBM), ExlService (IPO), Financial Engines (IPO), Fleet One (acquired by Wright Express), Mu Sigma (sold to shareholders), PowerShares (acquired by Invesco), Varicent (acquired by IBM) and Verus Financial Management (acquired by The Sage Group).

Contacts

FTV Capital

Karen Derr Gilbert, 415-229-3000

kgilbert@ftvcapital.com

www.ftvcapital.com









Permalink: http://me-newswire.net/news/10441/en

First Data Brings on First Developer Licensee for its VisionPLUS and AccessPLUS Suite of Products

Attra Becomes a Service Delivery Partner to Enhance Clients’ Experience

ATLANTA. - Tuesday, March 25th 2014 [ME NewsWire]

(BUSINESS WIRE) First Data Corporation, the global leader in payment technology and services solutions, has added Attra Infotech, a leading cards and payments services specialist, as its first Developer License Program member for the VisionPLUS and AccessPLUS suite of software products licensed by First Data globally.

VisionPLUS, is a payment processing solution for financial institutions that enables the issuance and processing of credit, debit, commercial and prepaid cards, as well consumer loans, loyalty and merchant accounts on a single platform. Offered with VisionPLUS is AccessPLUS with a suite of business process management products that drives operational staff efficiency in servicing customers and supports portfolio parameter management.

Attra Infotech becomes part of the international partner ecosystem that enables First Data to bring application support services and product innovation to our clients for the VisionPLUS and AccessPLUS licensed software products. First Data’s Developer License Program further contributes to keeping the VisionPLUS and AccessPLUS suite of products flexible and up-to-date with new market trends and technology.

“This initiative is designed to drive an improved client experience with reliable and consistent service,” said John Elkins, president, First Data International Regions. “By having Attra as our first licensed developer, VisionPLUS and AccessPLUS are now equipped with even more value-added services that can be offered to our clients.”

Under the agreement, Attra will be a systems integration partner to First Data internationally and will provide installation, implementation, portfolio migrations, business-as-usual support, development and testing services for the VisionPLUS and AccessPLUS suites of products.

“As a specialist cards and payments IT services company, Attra is pleased to be a strategic partner to First Data for their VisionPLUS and AccessPLUS suite of products,” said Prasad Guntupalli, Co-founder and CEO, Attra Infotech. “The partnership gives Attra a wider geographic reach and First Data’s licensed clients for these products will benefit from our deep domain expertise and access to First Data’s latest offerings and best practices.”

Those interested in joining the Developer License program should contact Eva Hughes, vice president of product management – Vision Payment Solutions, ateva.hughes@firstdata.com.

About First Data

Around the world, every second of every day, First Data makes payment transactions secure, fast and easy for merchants, financial institutions and their customers. First Data leverages its vast product portfolio and expertise to drive client revenue and profitability. Whether the choice of payment is by debit or credit card, gift card, check or mobile phone, online or at the checkout counter, First Data takes every opportunity to go beyond the transaction. More information about the company is available on FirstData.com as well as onTwitter, LinkedIn, Facebook and YouTube.

About Attra

Attra is a leading IT solutions and services provider with a deep focus on banking, finance and payments industry. With global delivery centers in Bangalore, Melbourne, Pune, and Dubai; we provide a broad range of IT services which include Advisory, Application Management, Independent Testing, System Transformation, System Integration, and Business Intelligence. Attra is a CMMI Level 3 Organization with enterprise wide PCI DSS certification. Attra’s team of over 800 professionals across the globe brings in unique expertise – a blend of technology and high domain & business process knowledge. More information about the company is available on www.attra.com.

Contacts

Cara Crifasi, First Data

303-967-6367

cara.crifasi@firstdata.com



Srini Nagasundram, Attra

+91 8040530825

srini.nagasundram@attra.com.au

Permalink: http://me-newswire.net/news/10442/en

PMI Expands Focus on Requirements Management

NEWTOWN SQUARE, Pa - Tuesday, March 25th 2014 [ME NewsWire]

(BUSINESS WIRE) According to PMI’s 2014 Pulse of the Profession® study, poor requirements management is a major cause of project failure, second only to changing organization priorities. In order to help project professionals and organizations overcome this challenge, Project Management Institute (PMI), the world's leading not-for-profit professional membership association for the project management profession, is expanding its requirements management offerings. The online Requirements Management Knowledge Center of Excellence and the Professional in Business Analysis (PMI-PBA)SM credential are launching today. PMI is also scheduled to publish a practice guide on the topic of business analysis and a full-consensus requirements management practice standard. Together, these and other new PMI resources will better position requirements management as a critical skill component, and aid professionals in successfully navigating increasingly complex projects.

Requirements Management Knowledge Center of Excellence

Reflecting PMI’s ongoing commitment to meeting the changing needs of practitioners and organizations, PMI has launched a new Requirements Management Knowledge Center of Excellence (CoE) web page at www.PMI.org/RequirementsManagement. This resource is designed to help practitioners and organizations improve their requirements management capabilities and maturity in order to improve project outcomes.

This Knowledge Center of Excellence extends to ProjectManagement.com, where practitioners new to requirements management will find answers to basic questions, content from subject matter experts as well as tools and templates. Visit that page at www.ProjectManagement.com/Practices/Requirements-Management.

Facing Next-Generation Challenges: The Business Need for the PMI-PBASM Credential

Developed with input from a broad group of expert professionals, PMI’s Professional in Business Analysis (PMI-PBA)SM credential is a solution to the critical business need for improving requirements management. The credential is designed around business research to address the specific role business analysis serves in defining an organization’s business requirements to ensure that projects and programs deliver expected benefits and meet business goals. With this credential, organizations will now be able to validate the skills, knowledge and competence of business analysis practitioners. Likewise, practitioners will be able to demonstrate their expertise, knowledge and experience in the role of business analysis to organizations. To learn more about the PMI-PBA credential and to participate in its pilot program, visit http://www.pmi.org/Certification/PMI-Professional-in-Business-Analysis-PMI-PBA.aspx.

More Requirements Management Resources

In addition to the Requirements Management COE and PMI-PBA credential, PMI plans to publish a practice guide on the topic of business analysis later in 2014. This practice guide will link good requirements management practices from A Guide to the Project Management Body of Knowledge (PMBOK® Guide) to the practice of business analysis within organizations. In addition, a full-consensus practice standard on the topic of requirements management is slated for launch in 2015. PMI has embarked on a collaborative effort with: project managers; value, software and systems engineers; and business and agile analysts to produce a practice standard focused on the common components of requirements across these disciplines.

“Working with practitioners and experts in the area of requirements management, PMI continues to help organizations and practitioners recognize the direct impact this critical competency has on the success of their programs and projects,” said Brian A. Weiss, PMI Vice President of Practitioner Markets. “The Requirements Management Knowledge Center of Excellence, the PMI-PBA credential, and other new PMI requirements management resources reaffirm our commitment to this aspect of the profession and will help organizations embed it as part of their core project management capability.”

About Project Management Institute (PMI)

Project Management Institute is the world's leading not-for-profit professional membership association for the project, program and portfolio management profession. Founded in 1969, PMI delivers value for more than 2.9 million professionals working in nearly every country in the world through global advocacy, collaboration, education and research. PMI advances careers, improves organizational success and further matures the profession of project management through its globally recognized standards, certifications, resources, tools academic research, publications, professional development courses, and networking opportunities. As part of the PMI family, Human Systems International (HSI) provides organizational assessment and benchmarking services to leading businesses and government, while ProjectManagement.com and ProjectsAtWork.com create online global communities that deliver more resources, better tools, larger networks and broader perspectives.

Visit us at www.PMI.org, www.facebook.com/PMInstitute and on Twitter @PMInstitute.

Contacts
PMI
Megan Maguire Kelly, +1 610-356-4600 x7030
Megan.Kelly@pmi.org









Permalink: http://www.me-newswire.net/news/10439/en

Toshiba Starts Sample Shipments of Regulator ICs for Automotive Applications

Supports High Output Current in Combination with an External Power Transistor

TOKYO - Tuesday, March 25th 2014 [ME NewsWire]

(BUSINESS WIRE)-- Toshiba Corporation (TOKYO:6502) today announced the launch of “TB9005FNG”, a 5-volt constant voltage regulator for application in automotive systems. Sample shipments start today, with mass production scheduled to start in December 2014.

“TB9005FNG” supports 1A or higher output current in combination with external power transistors1, allowing use in automotive applications that require high output current. The IC also incorporates system reset functions for reset of microcontrollers when their voltage is lowered or clock signals are cut off, which contributes to improved safety for automotive systems.

Applications

Automotive applications using 5-volt microcontrollers

Key Features

Part Number
         

TB9005FNG

Output Voltage
         

5.0V±0.15V

Operation Current
         

90μA (typ) (Vin=12V, Ta=25°C) at 5-volt output

System Reset Functions
         

Low-voltage reset, power-on reset, and watchdog timer

Low Voltage Detection
         

Threshold selectable either 4.2V (typ) or 4.7V (typ)

Current Limiter
         

Adjustable with external resistor

Operating Power Supply Voltage Range
         

6 to 18V

Operating Temperature Range
         

-40 to 125°C

Package
         

SSOP-20-P-225-0.65A


Note

1.
         

The product can supply more than 2A output current, when used with Toshiba power transistor “TTB002” or “TTA005”. Survey by Toshiba Corporation.


Customer Inquiries: Automotive Sales and Marketing Department Tel: +81-3-3457-3428

Information in this document, including product prices and specifications, content of services and contact information, is current on the date of the announcement but is subject to change without prior notice.

About Toshiba

Toshiba is a world-leading diversified manufacturer, solutions provider and marketer of advanced electronic and electrical products and systems. Toshiba Group brings innovation and imagination to a wide range of businesses: digital products, including LCD TVs, notebook PCs, retail solutions and MFPs; electronic devices, including semiconductors, storage products and materials; industrial and social infrastructure systems, including power generation systems, smart community solutions, medical systems and escalators & elevators; and home appliances.

Toshiba was founded in 1875, and today operates a global network of more than 590 consolidated companies, with 206,000 employees worldwide and annual sales surpassing 5.8 trillion yen (US$61 billion). Visit Toshiba's web site at www.toshiba.co.jp/index.htm

Photos/Multimedia Gallery Available: http://www.businesswire.com/cgi-bin/mmg.cgi?eid=50830147&lang=en

Contacts

Media Inquiries:

Toshiba Corporation

Semiconductor & Storage Products Company

Takashi Mochizuki, +81-3-3457-4963

semicon-NR-mailbox@ml.toshiba.co.jp









Permalink: http://www.me-newswire.net/news/10436/en

Shiseido Awarded World's Most Ethical Companies Designation Three Years in a Row

TOKYO - Tuesday, March 25th 2014 [ME NewsWire]

(BUSINESS WIRE)-- Shiseido Co., Ltd. (TOKYO:4911) has been selected and awarded the 2014 World’s Most Ethical Companies designation for the third consecutive year. The announcement was made on March 20, 2014 by Ethisphere® Institute, a U.S.-based international think-tank dedicated to advocating best practices in business in such areas as corporate ethics and corporate social responsibility (CSR).

In addition to strengthening governance and thoroughly adhering to sound corporate ethics, global companies are currently urged to address major management challenges by taking a leadership role concerning social and environmental issues while also ensuring profitable, sustainable growth. Shiseido considers that these consecutive awards indicate society’s evaluation for its initiatives toward “becoming a global player representing Asia with its origins in Japan”. Shiseido will not only promote management with even more transparency but also contribute to society through various corporate activities.

2014 World’s Most Ethical Companies

“Ethisphere® Institute” has been researching approximately 1,000 companies from over 100 countries worldwide and announcing the “World’s Most Ethical Companies” every year since 2007. To select these companies, Ethisphere® Institute conducts research based on 5 categories of (1) concept of corporate ethics and legal compliance, (2) activity contents as a corporate citizen, (3) evaluation by society, top management leadership, communication with stakeholders, (4) establishment of corporate ethics, and (5) corporate governance system.

Shiseido Corporate Ethics and Social Contribution Activities

For approximately 140 years since it was founded in 1872, Shiseido has been engendering the spirit of “Serving our customers through beauty and wellness” as a fundamental principle of its corporate activities. Also, cognizant that overseas sales currently account for approximately 50% of sales, Shiseido has reviewed and newly established the Shiseido Group corporate philosophy entitled “Our Mission, Values and Way” in April 2011 with the aim of enhancing the solidarity of the Shiseido Group. Specifically, with regard to corporate ethics, Shiseido is carrying out initiatives based on “Our Way,” which denotes action standards that each and every employee should take to earn the trust of 5 types of stakeholders, including “customers”, “business partners”, “shareholders”, “employees”, and “society/Earth”. As for social contribution activities, Shiseido is also promoting various initiatives by designating women and cosmetics (beauty), culture and the environment as the three priority domains in which Shiseido is able to leverage its strengths.

Photos/Multimedia Gallery Available: http://www.businesswire.com/cgi-bin/mmg.cgi?eid=50830220&lang=en

Contacts

Shiseido

Tatsuyoshi Endo, +81-3-3572-5111

PR department

tatsuyoshi.endo@to.shiseido.co.jp









Permalink: http://me-newswire.net/news/10437/en

Oral OTEZLA® (apremilast) Demonstrated Clinically Meaningful and Sustained Improvements in Skin, Nail and Scalp of Adult Patients with Moderate to Severe Plaque Psoriasis

ME Newswire / Business Wire

SUMMIT, N.J - Monday, March 24th 2014

OTEZLA demonstrated stable improvements in PASI response up to week 52 in ESTEEM 1 OTEZLA significantly improved signs and symptoms of psoriasis, including scalp and nails, compared with placebo in ESTEEM 2 at week 16, consistent with previously-reported ESTEEM 1 data Long term safety and tolerability profile in ESTEEM 1 was consistent with previously-reported long-term data from OTEZLA clinical trial programs No clinically meaningful changes in laboratory measurements compared with placebo observed in ESTEEM 1 or 2

Celgene Corporation (NASDAQ:CELG) today released new research findings on OTEZLA® (apremilast), the Company’s oral, selective inhibitor of phosphodiesterase 4 (PDE4), from the ESTEEM 1 and 2 phase III studies in patients with moderate to severe plaque psoriasis at the 72nd Annual Meeting of the American Academy of Dermatology (AAD) Annual Meeting in Denver, CO.

In ESTEEM 1 and 2 patients received OTEZLA 30 mg twice daily (BID) or placebo for the first 16 weeks, followed by a maintenance phase through week 32 in which patients on placebo for 16 weeks were switched to OTEZLA. Patients initially randomized to OTEZLA 30 mg BID and who were PASI 75 (psoriasis area and severity index) responders at week 32 were re-randomized to either OTEZLA 30 mg BID or placebo.

ESTEEM 1 demonstrated a stable mean PASI improvement of 81 to 88 percent between weeks 32 and 52 for those patients who were treated for 52 weeks with OTEZLA 30 mg BID and who achieved a PASI-75 score at week 32 (n=77). These data are consistent with the mean PASI-75 improvement observed between weeks 16 and 32.

In the same group of patients, OTEZLA 30 mg BID continued to demonstrate improvements in difficult-to-treat areas affected by plaque psoriasis. Among patients who had nail psoriasis at baseline (n=46), the majority showed meaningful improvement in their nails. A mean percent decrease from baseline in the Nail Psoriasis Severity Index (NAPSI) of 60.2 percent was observed at week 52. Of those patients who had scalp psoriasis defined as moderate or greater at baseline (n=49), the majority continued to demonstrate meaningful improvement in their scalp psoriasis with 72.9 percent having reduction of their scalp symptoms to clear or almost clear (ScPGA 0 or 1) at week 52.

In ESTEEM 2, a significantly higher percentage of patients receiving OTEZLA 30 mg BID achieved a PASI-75 response at week 16 (primary endpoint) compared with patients who received placebo (28.8 percent vs. 5.8 percent; p<0.0001). Statistical significance at week 16 was also demonstrated for the major secondary endpoint, static Physician Global Assessment (sPGA) score of clear or almost clear (p<0.0001).

The beneficial effects of OTEZLA on psoriasis in difficult-to-treat areas of scalp, nails, palms and soles were also demonstrated in ESTEEM 2. After 16 weeks of treatment, OTEZLA 30 mg BID demonstrated significantly higher response rates versus placebo for psoriasis affecting the scalp (ScPGA 0-1: 40.9 percent vs. 17.2 percent; p<0.0001), nails (NAPSI-50: 44.6 percent vs. 18.7 percent; p<0.0001), and palm and soles (Palmoplantar Physician Global Assessment (PPPGA) 0-1: 65.4 percent vs. 31.3 percent; nominal p=0.0315).

“Psoriasis of the nails, scalp and palmoplantar regions is very difficult to treat and can be debilitating for individuals dealing with this chronic disease," said Jennifer Cather, MD, Modern Research Associates, Dallas, Texas. “Results from the 52-week analysis of the ESTEEM program suggest that early responses seen with OTEZLA treatment in multiple efficacy endpoints of plaque psoriasis, including difficult to treat areas, are durable over time. Together with the observed long-term consistent safety and tolerability profile, these findings are encouraging.”

A separate analysis of long-term (52-week) safety and tolerability data from ESTEEM 1 identified no new or unexpected adverse events (AEs) for patients treated with OTEZLA compared with results at week 16. The most frequently reported AEs during the placebo-controlled period and the long-term 52-week OTEZLA-exposure period were diarrhea, upper-respiratory tract infection, nausea, nasopharyngitis, tension headache, and headache. Discontinuation rates for diarrhea and nausea were each less than 2 percent in the OTEZLA 30 mg BID group through week 52. No serious AEs of diarrhea and nausea were reported in all groups through 52 weeks. Serious AEs were similar between placebo and OTEZLA in the first 16 weeks, and the rate did not change through the 52-week OTEZLA-exposure period. No clinically meaningful changes in laboratory measurements were identified over the OTEZLA 52-week exposure period.

No new or unexpected AEs were identified for patients treated with OTEZLA in ESTEEM 2.

In a pooled analysis of ESTEEM 1 and 2, exposure-adjusted incidence rates (per 100 patient-years) for major adverse cardiac events, serious infections including systemic opportunistic infection, or malignancies were comparable between placebo and OTEZLA treatment groups.

OTEZLA is not indicated for the treatment of patients with psoriasis in any country.

OTEZLA was approved on March 21, 2014 by the U.S. Food and Drug Administration (FDA) for the treatment of adults with active psoriatic arthritis. A New Drug Submission (NDS) based on the combined data from the PALACE 1, 2 and 3 trials for psoriatic arthritis was submitted to health authorities in Canada in the second quarter of 2013. A New Drug Application (NDA) for psoriasis in the U.S., a NDS for psoriasis in Canada as well as a combined psoriatic arthritis/psoriasis Marketing Authorization Application (MAA) in Europe were all submitted to health authorities in the fourth quarter of 2013.

About ESTEEM 1 and 2

ESTEEM 1 and 2 are two large pivotal phase III randomized, placebo-controlled studies evaluating OTEZLA in patients with a diagnosis of moderate to severe plaque psoriasis for at least 12 months prior to screening, and who were also candidates for phototherapy and/or systemic therapy. Approximately 1,250 patients were randomized 2:1 to receive either OTEZLA 30 mg twice daily or placebo after an initial five-day titration period, for the first 16 weeks, followed by a maintenance phase from weeks 16-32 in which placebo patients were switched to OTEZLA 30 mg twice daily through week 32, and a randomized withdrawal phase for responders from week 32 to week 52 based on their initial OTEZLA randomization and PASI-75 response.

About OTEZLA

OTEZLA is an oral small-molecule inhibitor of phosphodiesterase 4 (PDE4) specific for cyclic adenosine monophosphate (cAMP). PDE4 inhibition results in increased intracellular cAMP levels.

INDICATION AND IMPORTANT SAFETY INFORMATION FOR ADULTS WITH PSORIATIC ARTHRITIS

INDICATION

OTEZLA® (apremilast) is indicated for the treatment of adult patients with active psoriatic arthritis.

IMPORTANT SAFETY INFORMATION

Contraindications

OTEZLA is contraindicated in patients with a known hypersensitivity to apremilast or to any of the excipients in the formulation.

Warnings and Precautions

Depression: Treatment with OTEZLA is associated with an increase in adverse reactions of depression. During clinical trials, 1.0% (10/998) of patients treated with OTEZLA reported depression or depressed mood compared to 0.8% (4/495) treated with placebo; 0.3% (4/1441) of patients treated with OTEZLA discontinued treatment due to depression or depressed mood compared with none in placebo treated patients (0/495). Depression was reported as serious in 0.2% (3/1441) of patients exposed to OTEZLA, compared to none in placebo treated patients (0/495). Suicidal ideation and behavior were observed in 0.2% (3/1441) of patients on OTEZLA, compared to none on placebo (0/495). Two patients who received placebo committed suicide compared to none on OTEZLA.

Carefully weigh the risks and benefits of treatment with OTEZLA for patients with a history of depression and/or suicidal thoughts/behavior, or in patients who develop such symptoms while on OTEZLA. Patients, caregivers, and families should be advised of the need to be alert for the emergence or worsening of depression, suicidal thoughts or other mood changes, and they should contact their healthcare provider if such changes occur.

Weight Decrease: Body weight loss of 5-10% was reported in 10% of patients taking OTEZLA and in 3.3% of patients taking placebo. Monitor body weight regularly; evaluate unexplained or clinically significant weight loss, and consider discontinuation of OTEZLA.

Drug Interactions: Apremilast exposure was decreased when OTEZLA was co-administered with rifampin, a strong CYP450 enzyme inducer; loss of OTEZLA efficacy may occur. Concomitant use of OTEZLA with CYP450 enzyme inducers (eg, rifampin, phenobarbital, carbamazepine, phenytoin) is not recommended.

Adverse Reactions

Adverse reactions reported in at least 2% of patients taking OTEZLA, that occurred at a frequency at least 1% higher than that observed in patients taking placebo, for up to 16 weeks (after the initial 5-day titration), were (OTEZLA%, placebo%): diarrhea (7.7, 1.6); nausea (8.9, 3.1); headache (5.9, 2.2); upper respiratory tract infection (3.9, 1.8); vomiting (3.2, 0.4); nasopharyngitis (2.6, 1.6); upper abdominal pain (2.0, 0.2).

Use in Specific Populations

Pregnancy and Nursing Mothers: OTEZLA is Pregnancy Category C; it has not been studied in pregnant women. Use during pregnancy only if the potential benefit justifies the potential risk to the fetus. It is not known whether apremilast or its metabolites are present in human milk. Caution should be exercised when OTEZLA is administered to a nursing woman.

Renal Impairment: OTEZLA dosage should be reduced in patients with severe renal impairment (creatinine clearance less than 30 mL/min); for details, see Dosage and Administration, Section 2, in the Full Prescribing Information.

Please click here for Full Prescribing Information.

About Psoriasis

Psoriasis is an immune-mediated, non-contagious chronic inflammatory skin disorder of unknown cause. The disorder is a chronic recurring condition which varies in severity from minor localized patches to complete body coverage. Plaque psoriasis is the most common type of psoriasis. About 80 percent of people who develop psoriasis have plaque psoriasis, which appears as patches of raised, reddish skin covered by silvery-white scales. These patches, or plaques, frequently form on the elbows, knees, lower back, and scalp. Psoriasis occurs nearly equally in males and females. Psoriasis is believed to be most common in Caucasians and slightly less common in other ethnic groups. Worldwide, psoriasis is most common in Scandinavia and other parts of northern Europe. An estimated 125 million people worldwide have psoriasis. To learn more about the role of PDE4 in inflammatory diseases, go to www.discoverpde4.com.

About Celgene

Celgene Corporation, headquartered in Summit, New Jersey, is an integrated global pharmaceutical company engaged primarily in the discovery, development and commercialization of innovative therapies for the treatment of cancer and inflammatory diseases through gene and protein regulation. For more information, please visit www.celgene.com.

Forward-Looking Statements

This press release contains forward-looking statements, which are generally statements that are not historical facts. Forward-looking statements can be identified by the words “expects,” “anticipates,” “believes,” “intends,” “estimates,” “plans,” “will,” “outlook” and similar expressions. Forward-looking statements are based on management’s current plans, estimates, assumptions and projections, and speak only as of the date they are made. We undertake no obligation to update any forward-looking statement in light of new information or future events, except as otherwise required by law. Forward-looking statements involve inherent risks and uncertainties, most of which are difficult to predict and are generally beyond our control. Actual results or outcomes may differ materially from those implied by the forward-looking statements as a result of the impact of a number of factors, many of which are discussed in more detail in our Annual Report on Form 10-K and other reports filed with the Securities and Exchange Commission.

Contacts

Celgene Corporation

Investors:

Patrick E. Flanigan III, 908-673-9969

Vice President, Investor Relations



Media:

Catherine Cantone, 732-564-3592

Director, Corporate Communications







Permalink: http://me-newswire.net/news/10425/en